Punicalagin - Technical
Punicalagin
CAS: 65995-63-3
Molecular Formula: C48H28O30
Punicalagin - Technical - Names and Identifiers
| Name | Punicalagin |
| Synonyms | Punicalagin Punicalagins Pomegranate extract PULCHINENOSIDE B4(RG) Punicalagin - Technical D-Glucose, cyclic 4,6-(2,2'-(5,10-dihydro-2,3,7,8-tetrahydroxy-5,10-dioxo(1)benzopyrano(5,4,3-cde)(1)benzopyran-1,6-diyl)bis(3,4,5-trihydroxybenzoate)) cyclic 2,3-(4,4',5,5',6,6'-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate)-, (2(S),4(S,S))- |
| CAS | 65995-63-3 |
| InChI | InChI=1/C48H28O30/c49-5-16-40(76-46(70)20-7(1-11(50)30(58)34(20)62)17-8(44(68)74-16)2-12(51)27(55)31(17)59)39-15(54)6-73-43(67)9-3-13(52)28(56)32(60)18(9)21-25-23-24-26(48(72)78-41(23)37(65)35(21)63)22(36(64)38(66)42(24)77-47(25)71)19-10(45(69)75-39)4-14(53)29(57)33(19)61/h1-5,15-16,39-40,50-66H,6H2 |
| InChIKey | ZJVUMAFASBFUBG-UYMKNUMKSA-N |
Punicalagin - Technical - Physico-chemical Properties
| Molecular Formula | C48H28O30 |
| Molar Mass | 1084.72 |
| Density | 2.076±0.06 g/cm3(Predicted) |
| Melting Point | >155°C (dec.) |
| Specific Rotation(α) | (c, 1.0 in H2O)-181；(c, 0.9 in MeOH)+3.8 |
| Solubility | Soluble in water, soluble in methanol, ethanol and other organic solvents. |
| Appearance | Green yellow powder |
| Color | faint yellow to dark yellow |
| pKa | 1.92±0.60(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 2 months. |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.893 |
| MDL | MFCD09838017 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Punica granatum Linn.. |
| In vitro study | Punicalagin (100 mg/ml) induces apoptosis in HT-29, HCT116 colon cells. |
| In vivo study | Punicalagin (10 mg/kg) inhibits the edema rate of 58.15% in rats. |
Punicalagin - Technical - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29389090 |
Punicalagin - Technical - Reference
| Reference Show more | 1. Liu, Shen, Wang, Li, et al. Optimization of the separation and purification process of punicyanoside from pomegranate peel [J]. China pharmacist 2017 20(001):14-19. 2. Song Xiaoling, Yan Yan, Zheng Sicong, etc. Establishment of HPLC fingerprint of Mongolian medicine Anari Siwei powder and determination of main index components [J]. Journal of Chinese medicine for ethnic minorities, 2019, 30 (7):45-47. 3. Li, P, Du, R, Chen, Z, et al. Punicalagin is a neuraminidase inhibitor of influenza viruses. J Med Virol. 2021; 93: 3465- 3472. https://doi.org/10.1002/jmv.26449 4. [IF = 7.514] Junwei Cao et al."Number of galloyl moiety and intramolecular bonds in galloyl-based polyphenols affect their interaction with alpha-glucosidase."Food Chem. 2022 Jan;367:129846 5. [IF=6.684] Gulinigaer Anwaier et al."Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5."Front Cell Dev Biol. 2021; 9: 697539 6. [IF=5.396] Junwei Cao et al."Number of galloyl moieties and molecular flexibility are both important in alpha-amylase inhibition by galloyl-based polyphenols."Food Funct. 2020 May;11(5):3838-3850 7. [IF=2.408] Amit Jaisi et al."Investigation of HIV-1 Viral Protein R Inhibitory Activities of Twelve Thai Medicinal Plants and Their Commercially Available Major Constituents."Chemistry & Biodiversity. 2021 Oct 27 8. [IF=2.327] Ping Li et al."Punicalagin is a neuraminidase inhibitor of influenza viruses."J Med Virol. 2021 Jun;93(6):3465-3472 9. [IF=6.576] Guowei Man et al."Profiling Phenolic Composition in Pomegranate Peel From Nine Selected Cultivars Using UHPLC-QTOF-MS and UPLC-QQQ-MS."Front Nutr. 2021; 8: 807447 |
Punicalagin - Technical - Reference Information
| Plant Source: | pomegranate |
| biological activity | Punicalagin is a species derived from pomegranate (Punica granatum L.) or Terminalia catappa L. The leaves of the isolated polyphenol components. Punicalagin is an anti-hepatitis B Virus (HBV) drug that has antioxidant, anti-inflammatory and anti-cancer effects. |
| Use | the effect of anti-inflammatory, analgesic, hypnotic and anticonvulsant anticancer, antioxidant. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: has a strong anti-oxidation, anti-tumor and anti-atherosclerosis role. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:52:54
Supplier List
Featured ProductsSpot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Featured ProductsSpot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: +86-(0)731-84213302
Email: sales@staherb.cn
Mobile: +86 13875855783
QQ: 484702402
WhatsApp: +86 18374838656
Linkedin: +86 18374838656
Spot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Punicalagin Request for quotation
CAS: 65995-63-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 65995-63-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Featured ProductsSpot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Featured ProductsSpot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: +86-(0)731-84213302
Email: sales@staherb.cn
Mobile: +86 13875855783
QQ: 484702402
WhatsApp: +86 18374838656
Linkedin: +86 18374838656
Spot supply
Product Name: Punicalagin Visit Supplier Webpage Request for quotationCAS: 65995-63-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Punicalagin Request for quotation
CAS: 65995-63-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 65995-63-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History